Recovery begins before the injection

A regenerative treatment is more than just PRP, BMAC, or another autologous product. The condition of the tissue, your biological baseline, and the subsequent support also determine how recovery progresses.

Prepare
the biological soil

Personalize
product and dosage

Support
recovery and rehabilitation

Preparing the soil

We prepare the soil

Two people with a similar diagnosis can react very differently to the same treatment. Recovery does not depend solely on the local injury. Nutrition, metabolic health, sleep, stress, exercise, and low-grade inflammation can also influence how the body responds.

Preparing the soil means we first look at which conditions might hinder recovery, and which of those we can specifically improve.

Hand placing a small tube with a green cap into a laboratory centrifuge machine.

What does your recovery need?

Through the Clinical Profile, we determine which factors truly require your attention.

Nutrition and relevant deficiencies

Sleep and stress regulation

Movement and resilience

Photobiomodulation

Metabolic optimization

GLP-1 treatment if indicated

Through the Clinical Profile, we determine which factors truly require attention in your case.

Medical background

Metabolic dysregulation can coincide with systemic low-grade inflammation, oxidative stress, vascular changes, and an impaired cellular response. Insulin resistance, hyperglycemia, dyslipidemia, excess fat mass, sleep deprivation, and nutritional deficiencies can therefore also influence the local recovery environment.

The literature describes this metabolically driven inflammatory process as meta-inflammation. The clinical significance varies per patient and condition. Therefore, we do not use these factors as a fixed package, but as part of an individual medical assessment.

Not every PRP treatment is the same

Autologous means that the biological product is prepared from your own body. But the name PRP or BMAC does not tell you exactly what a patient is receiving. Starting material, preparation method, composition, volume, and dose can vary significantly.

That is why we tailor the product and administration to the diagnosis, the tissue being treated, the severity of the damage, previous treatments, and your recovery capacity.

Een persoon trekt vloeistof met een injectienaald uit een flesje voor medicatie.

Een persoon krijgt een injectie in de knie, toegediend door iemand die paarse handschoenen draagt.

High-dose PRP

The total platelet dose counts

We look not only at the concentration per milliliter, but at the total amount of platelets delivered to the target area.

For us, high dose means a purposefully prepared and sufficiently dosed product — not simply as much as possible.

Medical background

Research into the clinical dose-response of PRP is currently most advanced for knee osteoarthritis. These data cannot be directly translated to every other joint or tissue. However, they do support the broader principle that a biological product must be adequately characterized and dosed for its intended purpose.

In addition to the total platelet dose, the injection volume, concentration factor, leukocyte profile, any red blood cells present, and plasma composition can be significant. Age, health, medication, and lifestyle can also influence the starting product.

An environment where recovery components work together

Tissue repair occurs through the interaction between platelets, plasma proteins, signaling molecules, local cells, and the matrix in which these components function.

That is why, for more complex treatments, we look not only at what we concentrate, but also at how we can bring biological components together locally.

Platelets

concentrated biological signals

Plasma proteins

including fibrinogen and A2M

Healing matrix

temporary biological platform

More than just platelets

By combining a highly concentrated platelet fraction with concentrated plasma proteins, a fibrin-rich network can be formed after activation. This temporary autologous matrix can locally retain biological components and support their interaction.

The potential role of BMAC

For selected, typically more complex conditions, BMAC can be used as an additional autologous component. BMAC contains a mixed bone marrow-derived population of cells, platelets, and signaling molecules. It is not a pure stem cell product.

Medical insights

Everts, Podesta, and co-authors describe a protein-rich, platelet-rich plasma matrix in which a highly concentrated platelet fraction is combined with concentrated plasma proteins, including fibrinogen, albumin, and alpha-2-macroglobulin.

Upon activation, fibrinogen forms a three-dimensional network capable of locally retaining cellular and molecular components. During natural fibrinolysis, these can be gradually released. The potential addition of BMAC is a separate clinical treatment choice; clinical evidence for various combinations and indications is still evolving.

The regenerative pathway

From diagnosis to supported recovery

The injection is not an isolated product, but a carefully chosen step within a personalized plan.

1 Diagnosis and selection

Which structure is causing the symptoms, and is a regenerative treatment medically appropriate?

2 Clinical Profile

Which biological and functional factors influence your recovery and resilience?

3 Preparation

We address relevant barriers to recovery and prepare the tissue in a targeted manner.

4 Personalized intervention

We determine the product, composition, and dosage, and perform the treatment precisely under image guidance.

5 Stabilization and rehabilitation

Load, movement, local support, and follow-up are aligned with the biological recovery phase.

Would you like to know which approach is right for you?

A regenerative medical consultation begins with an accurate diagnosis and an honest discussion about options, alternatives, and expectations.

Schedule a medical consultation +32 (0) 16 18 58 52